2.4-D, aminopyralid and chloryralid, atrazine, dicamba, glyphosate, indaziflam, Isoxaflutole, picloram, pre-harbvest herbicides, sulfonylurea herbicides, triclopyr

see also digestive tract

Common Herbicide Contributes to Development of Inflammatory Bowel Disease    (Beyond Pesticides, October 25, 2022) Inflammatory bowel disease (IBD) may be exacerbated by exposure to the herbicide propyzamide, used in both agriculture and on ornamental lawns and landscapes, according to research published in the journal Nature this month.  Recent data show that the number of people living with Crohn’s disease and ulcerative colitis, common types of IBD, have risen annually by 3.4% and 2.8% respectively, between just the years 2001 to 2018.   (S)cientists cross-referenced data from the U.S. Environmental Protection Agency’s ToxCast database to screen hundreds of different chemicals that had an affect on intestinal inflammation. Ultimately, 20 candidate chemicals were found, and scientists decided to focus on propyzamide due to its broad use patterns in food and in residential areas.   Using a mouse model, scientists found that propyzamide worsened an inflammatory process that had already been triggered by another exposure, but did not initiate the inflammation.    SNAP Comment: As of 4 Nov 2022, there are only 3 propyzamide herbicides registered with the PMRA. Historically there were 5. There are sstill 18 registered formulations in the US. There is only one commercial one, wht a registration expiring in 2026. It is used for control of weeds in alfalfa, trefoil, ornamentals, strawberries, apples, pears, lowbush blueberries, lettuce and established pastures.