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Arthritis
also see Health/Inflammation, pyrethrins
Popular Pyrethroid Insecticides, Already Linked to Rheumatoid Arthritis, Associated with Osteoarthritis (Beyond Pesticides, September 20, 2023) Higher concentrations of a pyrethroid metabolite (3-PBA) in the body have an association with increased osteoarthritis (OA) risk among US adults, according to a study published in BMC Public Health. Regardless of analysis sensitivity and population subgroup (e.g., sex, socioeconomic status, etc.), the association between pyrethroid exposure and OA remains. The results demonstrate that the higher the levels of urinary 3-PBA, the greater the odds of OA in U.S. adults, highlighting the importance of routinely monitoring pyrethroid exposure among the general population. This study is one of the first to identify the association between chronic exposure to pyrethroids and OA. The study suggests pyrethroids’ adverse impact on thyroid hormones plays a significant role in OA development, affecting cell secretions of cartilage and enzyme activity in joints.