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Low Dose Effects
see also Health/Nervous System Effects/ Parkinson Disease, Loss of Smell, glyphosate, terrestrial invertebrates
Study first to link weed killer Roundup to convulsions in animals (Florida Atlantic University, 23 August, 2022) 'Results, published in Scientific Reports, showed that glyphosate and Roundup increased seizure-like behavior in soil-dwelling roundworms and provides significant evidence that glyphosate targets GABA-A receptors. These communication points are essential for locomotion and are heavily involved in regulating sleep and mood in humans. What truly sets this research apart is that it was done at significantly less levels than recommended by the EPA and those used in past studies. "The concentration listed for best results on the Roundup Super Concentrate label is 0.98 percent glyphosate, which is about 5 tablespoons of Roundup in 1 gallon of water," said Naraine. "A significant finding from our study reveals that just 0.002 percent glyphosate, a difference of about 300 times less herbicide than the lowest concentration recommended for consumer use, had concerning effects on the nervous system." "As of now, there is no information for how exposure to glyphosate and Roundup may affect humans diagnosed with epilepsy or other seizure disorders," said Dawson-Scully. "Our study indicates that there is significant disruption in locomotion and should prompt further vertebrate studies."' see also New Evidence Shows Roundup Damages the Nervous System (Beyond Pesticides, August 30, 2022)
Implications for Human Health: Chronic Inhalation of Paraquat in Low-Doses Disrupts Sense of Smell SNAP Comment: As of 9 March 3021, the PMRA still lists 3 paraquat labels as being registered in Canada. The commercial product is Gramoxone 200 SL. (Beyond Pesticides, February 18, 2021) 'New research published in the journal Toxicological Sciences finds extended inhalation of the common herbicide paraquat causes male mice to lose some sense of smell, even at low doses. This study highlights the significance of understanding how specific chemical exposure routes can influence disease development. Olfactory (relating to the sense of smell) impairment is a precursory feature of Parkinson’s disease (PD), and studies connect paraquat poisoning to PD risk.'