Glyphosate Breakdown Product, Associated with Oxidative Stress and DNA Damage Among Children    (Beyond Pesticides, April 28, 2022) 'A study in Environmental Research finds that glyphosate’s primary metabolite (breakdown product), aminomethylphosphonic acid (AMPA), induces DNA damage through oxidative stress among subpopulations of primary school children. The results find that AMPA, but not glyphosate, has a positive association with DNA damage via oxidation. Moreover, the metabolites of pyrethroids (3-PBA) and chlorpyrifos (TCPy) are also associated with DNA damage and oxidative stress. Lipid damage from oxidative stress did not occur among these pesticides. However, the results suggest parental education levels influence urinary pyrethroid levels. ...Glyphosate degrades relatively quickly in the environment, between five and 20 days, leaving behind AMPA, which is highly persistent with a half-life of 151 days.  SNAP Comment: As illustrated here, AMPA, the byproduct of glyphosate, persists a lot longer in the environment. This is not a unique case. Not only can degradation byproducts persisit  longer, they can also be more toxic than the original product. Current registration regulations generally overlook the effects of byporducts.

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